Thursday, May 4, 2017

Cancer-causing virus masters cell's replication & immortality quoting : drugtargetreview

"The virus actually taps into the B cell's normal protection against apoptosis," the programmed cell death that takes B cells out of circulation, Luftig said. The key piece they've uncovered is a viral protein called EBNA3A which manages apoptosis resistance in infected B cells. But few human viruses make themselves quite as cozy as the Epstein-Barr virus, which can be found in an estimated 9/10 humans without causing any ill effects. Cancer-causing virus masters cell's replication & immortality0 SHARESPosted: 4 May 2017 | Niamh Marriott (Junior Editor: addiction Target Review) |Viruses are notorious for taking over their host's operations and using them to their own advantage. Once the infection is established, Epstein-Barr prefers to hide out in what are known as "memory B cells," relatively slowly reproducing cells that circulate throughout the body.



Cancer-causing virus masters cell's replication & immortality

Cancer-causing virus masters cell's replication, immortality

"The virus actually taps into the B cell's normal protection against apoptosis," the programmed cell death that takes B cells out of circulation, Luftig said. The key piece they've uncovered is a viral protein called EBNA3A which manages apoptosis resistance in infected B cells. The Epstein-Barr virus takes control of the body's immune B-cells so that it can hide in plain sight. But few human viruses make themselves quite as cozy as the Epstein-Barr virus, which can be found in an estimated nine out of ten humans without causing any ill effects. Once the infection is established, Epstein-Barr prefers to hide out in what are known as "memory B cells," relatively slowly reproducing cells that circulate throughout the body.


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