Human Challenge Study Nixed for Zika Vaccine (STAT) according to : MedPage Today

A federal ethics panel has turned down a proposal from a group of researchers who sought to conduct a human challenge study – in which individuals are deliberately infected -- for a vaccine against the Zika virus, according to a report in STAT. That approach allows the effects of a vaccine for the prevention of transmission of the virus from a pregnant woman to her fetus to be tested in a concentrated fashion. However, the panel raised concerns about the possibility of third-party harm, such as through sexual contact with a person who had not volunteered for participation. The vaccine researchers could address the ethical problems by adapting their study protocol, for instance through enrolling women who are past reproductive age or examining post-infection consequences in previously infected individuals, suggested Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases. 2017-02-28T17:01:54-0500




In Philadelphia in 1964, a determined young physician and virologist named Stanley Plotkin began racing to make a rubella vaccine before the next epidemic. I am not talking about the Zika virus that, as of February 2, has led to the births of at least 2,656 infants with brain damage in 28 countries. In the US, it is still produced in Hayflick's fetal cells; it is the "R" in the "MMR" vaccine given to toddlers. The NIH's inscrutable vaccine czar was silently, inveterately opposed to making vaccines in Hayflick's human fetal cells. What followed was a thoroughly politicized vaccine race, in which Plotkin's superior vaccine was sidelined in favor of the in-house NIH candidate.

Vaccine that reacts to mosquito saliva tested to prevent Zika

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