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Gilead's Truvada OK'd in Europe to reduce risk of HIV infection - Gilead Sciences, Inc. (NASDAQ:GILD)
Gilead's Truvada OK'd in Europe to reduce risk of HIV infection - Gilead Sciences, Inc. (NASDAQ:GILD)
As expected, the European Commission approves Gilead Sciences' (GILD -0.2% ) TRUVADA (emtricitabine 200mg/tenofovir disoproxil 245mg; FTC/TDF), in combination with safer-sex practices, to reduce the risk of sexually acquired HIV-1 infection in uninfected adults.The approach is called pre-exposure prophylaxis.The approval follows a positive Ad Comm opinion last month.
furthermore indiatimes
Depression in HIV patients may increase risk of heart attack
Depression in HIV patients may increase risk of heart attack
NEW YORK: Human immuno-deficiency virus (HIV)-infected individuals already suffering from depression are at an increased risk of experiencing a heart attack than those without the mental health condition, finds a study.The findings showed that HIV-infected patients with major depressive disorder (MDD) -- a mood disorder causing a persistent feeling of sadness and loss of interest -- had a 30 per cent greater risk of having an acute myocardial infarction (AMI) or heart attack.With the advent of highly effective antiretroviral therapy and improved survival, people with HIV-infection are living longer.However, they are now at an increased risk of cardiovascular diseases (CVD).This elevation in heart attack risk decreased by 25 per cent after further adjustment for other variables, such as hepatitis C infection, kidney disease, alcohol or cocaine abuse or dependence and haemoglobin levels, the study said."Our findings raise the possibility that similar to the general population, MDD may be independently associated with incident atherosclerotic CVD in the HIV-infected population," said Matthew S. Freiberg of the Vanderbilt University School in the US.There is an urgent need to identify novel risk factors and primary prevention approaches for CVD in HIV, the researchers concluded in the paper published online by JAMA Cardiology.For the study, the team included 26,144 HIV-infected veterans without heart disease at baseline (1998-2003) participating in the US Department of Veterans Affairs 'Veterans Aging Cohort Study' from April 2003 through December 2009.
additionally aidsmap
HIV not a risk factor for fibrosis progression in people with hepatitis C
HIV not a risk factor for fibrosis progression in people with hepatitis C
HIV co-infection is not associated with accelerated progression of liver fibrosis in people with hepatitis C virus (HCV) infection, according to US research published in the online edition of the Journal of Infectious Diseases.Factors linked with fibrosis progression were low fibrosis stage at baseline and flares in alanine aminotransferase (ALT) levels.The major strengths of the study were its large sample size and the fact that participants had at least two liver biopsy results during follow-up, Dr Daniel S Frierer of Mount Sinai Hospital, New York, commented in an accompanying editorial.
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