Zika could be used for handling aggressive human central nervous system tumors, shows research
A Brazilian research published April 26 in the journal Cancer disease Research shows for the premier time in vivo which Zika could be used as a tool to treat aggressive human central nervous system (CNS) tumors. Extremely we had the idea of investigating whether the virus too attacked tumour stem cells in the central nervous system," he said. The experiments were performed by 3 human tumour cell lines: 2 derived from medulloblastoma & the 3rd from atypical teratoid/rhabdoid tumour (AT/RT). "The neural stem cells which undergo these alterations give height to tumour cells at a later phase. The 2nd experiment consisted of comparing Zika's capacity to infect healthful neural stem cells obtained from induced pluripotent stem cells (adult cells reprogrammed in the lab to behave such as stem cells) by its contagion of CNS tumour stem cells.Zika eliminates features human tumour in central nervous system of rodents: A group of Brazilian investigators approved for the first time in vivo the efficiency of Zika in infecting CNS tumour
as informed in Extremely we had the idea of investigating whether the virus too attacked tumour stem cells in the central nervous system," he said. The experiments were performed by 3 human tumour cell lines: 2 derived from medulloblastoma & the 3rd from atypical teratoid/rhabdoid tumour (AT/RT). "The neural stem cells which undergo these alterations give height to tumour cells at a later phase. The 2nd experiment consisted of comparing Zika virus's capacity to infect healthful neural stem cells obtained from induced pluripotent stem cells (adult cells reprogrammed in the lab to behave such as stem cells) by its contagion of CNS tumour stem cells. "We infective both cell types in vitro & found tumour stem cells to be even further susceptible to destruction by Zika virus than healthful neural stem cells," Okamoto said.collected by :Lucy William
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