How Zika Went From Mild to Devastating
By Dennis ThompsonHealthDay ReporterTHURSDAY, Sept. 28, 2017 (HealthDay News) -- A single genetic mutation only a few years back gave the Zika the ability to cause severe neurological birth defects such as microcephaly, a Fresh research in mice suggests. Scientists have known about the Zika ever ever 1947, while it was disclosed in a monkey from the Zika Forest in Uganda. The Chinese team, whose premier author is Ling Yuan of the Chinese Academy of Sciences in Beijing, compared 3 current Zika strains versus an older strain isolated in Cambodia in 2010. Comparing the strains, investigators found a critical mutation which altered a key protein in the protective coating of newer Zika viruses. This single change greatly enhanced Zika's ability to infect, damage & destroy human precursor brain cells, they said.Genetic Mutation Made Zika further Dangerous, research Says
as declared in We Utilize cookies & browser capability checks to help America deliver our on-line services, including to learn if you enabled Flash for vidimus or advertisement blocking. By Utilizing our website or with closing this message box, you agree to our Utilize of browser capability checks, & to our Utilize of cookies as described in our Cookie Policy .The Zika Grew Deadlier by a Small Mutation, research Suggests
The study, by scholars in China, found that strains of Zika by the S139N mutation caused substantially further dying & microcephaly in mice than other strains. "It's potentially important, & it's provocative," said David H. O'Connor, head of universal infectious illnesses at the University of Wisconsin-Madison's primate center, that has tested the Zika in monkeys. Then the team made 7 strains of the Zika virus, each by 1 mutation. In mouse embryos, the S139N mutation caused further severe microcephaly & dead brain cells. Did it confer a survival advantage to the Zika or only incidentally promote the virus's ability to cause microcephaly?Zika Virus Gene Mutation probably Cause Birth Defects
collected by :Sandra Alex
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