sciencedaily : declared in Previous bacterial infection increases risk of newly-diagnosed Sjögren's syndrome: Identifying trigger will hopefully help future development of targeted therapy for patients suffering from this debil

The magnitude of the association between NTM and SjS risk was greatest among those patients aged between 45 and 65 years. No association was found between SjS and a previous TB infection. However, the other four subjects were diagnosed on average 2.9 years after NTM infection. "Because SjS is a disease of insidious onset, we can't exclude the possibility that it may have occurred before the NTM infection. "Identifying NTM as one of the triggers will hopefully provide a clue to the future development of a targeted therapy for these patients," he added.

Deep perioperative infection risk after THA was greater with higher HbA1c levels

They were most interested in deep periprosthetic joint infection (PJI) within 1 year of surgery as an outcome, Browne noted. "When we developed our [receiver operating characteristic] ROC curve, we found the inflection point is around 7.0 [mg/dL] to 7.5 mg/dL," Browne said in his presentation. Predicting infection riskAlthough a patient's HbA1c correlated with the risk of infection after THA, Browne told Orthopedics Today that was a poor predictor of who would go on to develop an infection. "As we look at patients who have diabetes, the A1c is an important way to risk stratify patients," Browne said. The investigators found the patients with a HbA1c level below 7.5 mg/dL had a PJI rate of 1% vs. 2.4% in patients with a HbA1c level above 7.5 mg/dL.


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VIRUSES and INFECTIONS