Scientists have managed to get rid of HIV in mice according to : The Tech Portal

In what could be a huge milestone in the eventual eradication of AIDS in humans, scientists have managed to remove the HIV virus from mouse cells using CRISPR technology. So, a technology successful with mice has the potential to be successful with humans as well. Scientists have already tested the technology with mice and it has succeeded. What's more, due to the existence of latent reservoirs, in which HIV proviral DNA integrates in the host genome, the HIV viral load can rebounds and cause a catastrophic resurgence of HIV/AIDS as well. As mammals themselves, mice are only a few rungs below humans on the evolutionary ladder.




Researchers at Temple University in Philadelphia and the University of Pittsburgh said they used the CRISPR gene editing technology to remove HIV DNA from the genetic code of mice, eliminating the disease for the animals. This is the first study to use the CRISPR gene-editing technology to halt HIV replication and shut down the virus in animal cells. Eric MackScientists say they've used a gene-editing technique to cure mice of HIV. The study builds on years of research that initially showed that the AIDS virus and HIV could be cut from cells in lab dishes. CRISPR technology is still relatively new and has never been used to edit human genes.

Scientists have eliminated HIV in mice using CRISPR

Scientists have found they can successfully snip out the HIV virus from mouse cells using CRISPR/Cas9 technology. First published in the journal Molecular Therapy, the team is the first to show HIV can be completely annihilated from the body using CRISPR. But, should the scientists be able to replicate their findings, the technique could move to human trials in the future. However, CRISPR/Cas9 can be programmed to chop out any genetic code in the body with scissor-like precision, including, possibly, all HIV-1 DNA within the body. After just one treatment, scientists were able to show the technique had successfully removed all traces of the infection within mouse organs and tissue.


collected by :Lucy William
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