KFGO : reported that Prior exposure to dengue or West Nile could make Zika worse: report

By Julie SteenhuysenCHICAGO (Reuters) - Prior infection with West Nile or dengue - two viruses closely related to Zika - can make Zika symptoms worse, U.S. researchers said on Thursday. That could explain higher rates of severe Zika side effects, such as the birth defect microcephaly, in areas such as Brazil, where dengue is common. Symptoms were worst among Zika-infected mice that were given dengue antibodies, with only 21 percent of the mice surviving. The findings in mice, published in the journal Science, confirm studies in cells suggesting that prior infection with dengue could worsen the effects of Zika. That compared with survival rates of 93 percent among mice infected with Zika alone.

Prior exposure to dengue or West Nile could make Zika worse —report

Previous Infection With Dengue Or West Nile Viruses Could Worsen Zika Infection, Study In Mice Shows

Previous Infection With Dengue Or West Nile viruses Could Worsen Zika Infection, Study In Mice ShowsReuters: Prior exposure to dengue or West Nile could make Zika worse: report"Prior infection with West Nile or dengue — two viruses closely related to Zika — can make Zika symptoms worse, U.S. researchers said on Thursday. Similar results were reported in mice that received antibodies from West Nile patients…" (Berman, 3/30). Another group of animals received antibodies from 146 individuals with West Nile virus. The findings in mice, published in the journal Science, confirm studies in cells suggesting that prior infection with dengue could worsen the effects of Zika…" (Steenhuysen, 3/30). VOA News: Study: Prior Dengue Infection May Make Zika Worse"…In the study of mice, researchers at the Icahn School of Medicine at Mount Sinai in New York gave the rodents human antibodies to dengue virus from 141 infected individuals.


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