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New antibody may protect against Zika virus infection: Study
New antibody may protect against Zika virus infection: Study
Researchers, including one of Indian origin, have identified a human antibody that in pregnant mice prevents the foetus from becoming infected with Zika virus and damaging the placenta.Zika is a mosquito-borne virus that has emerged as a global public health threat.The antibody, called ZIKV-117, also protected adult mice from Zika disease, the researchers said.
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Hopes raised that Zika virus could be treated in the womb
Hopes raised that Zika virus could be treated in the womb
A Zika infection in pregnancy can cause birth defects"Scientists say they may have found a way to protect babies in the womb from the harmful effects of Zika," BBC News reports.Researchers have had success using antibody therapy to treat mice when they were still in their mothers' womb.There is evidence that Zika virus, which has become widespread in South America recently, can damage the development of babies in the womb.
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Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice
Neutralizing human antibodies prevent Zika virus replication and fetal disease in miceAbstract •Main •Author informationZika virus (ZIKV) is an emerging mosquito-transmitted flavivirus that can cause severe disease, including congenital birth defects during pregnancy1.To develop candidate therapeutic agents against ZIKV, we isolated a panel of human monoclonal antibodies (mAbs) from subjects with prior ZIKV infection.A subset of mAbs recognized diverse epitopes on the envelope (E) protein and exhibited potently neutralizing activity.
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