Experiment in monkeys raises hopes of 'functional cure' for HIV : foxnews

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Experiment in monkeys raises hopes of 'functional cure' for HIV

Experiment in monkeys raises hopes of 'functional cure' for HIV

A new drug combination helped stave off a monkey version of HIV for nearly two years after stopping all treatments, raising hopes for a functional cure for HIV, U.S. researchers said on Thursday.The treatment involved standard HIV drugs, known as antiretroviral therapy or ART, plus an experimental antibody that hits the same target as Takeda Pharmaceutical's Entyvio, a drug approved in more than 50 countries for ulcerative colitis and Crohn's disease.The findings, published Thursday in the journal Science, are promising enough that scientists at the National Institutes of Health, which funded the research, have already begun testing the Takeda drug, known generically as vedolizumab, in people newly infected with HIV.


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By adding an antibody to HIV treatment, researchers send virus into 'sustained remission' in monkeys

By adding an antibody to HIV treatment, researchers send virus into 'sustained remission' in monkeys

Scientists may have found a way for patients with HIV to keep the virus in check without having to take powerful drugs every day for the rest of their lives.A clinical trial in monkeys found that by augmenting the standard HIV treatment with an antibody developed in the lab, the animals were able to enter a state of sustained remission, according to a report in Friday's edition of the journal Science.All eight monkeys that tested the regimen were able to keep the virus at low or undetectable levels for at least nine months after the treatment ended.


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A new antibody therapy appears to have permanently blocked HIV infection in monkeys

A new antibody therapy appears to have permanently blocked HIV infection in monkeys

A new type of antibody therapy appears to have completely blocked the primate equivalent of HIV in infected monkeys.More than two years after the treatment, the monkeys are now drug free, have no symptoms, and there are almost no traces of the virus in their systems.The results are so impressive that clinical trials have already begun with human patients in the US.

By adding an antibody to HIV treatment, researchers send virus into 'sustained remission' in monkeys