Wednesday, August 24, 2016

Minimizing risk poses unique challenges in Zika vaccine trials, scientists say : foxnews





as mentioned in foxnews

Minimizing risk poses unique challenges in Zika vaccine trials, scientists say

Minimizing risk poses unique challenges in Zika vaccine trials, scientists say
Minimizing risk poses unique challenges in Zika vaccine trials, scientists say
As health officials fight to suppress a rising number of Zika virus cases in Florida, scientists with the National Institutes of Health (NIH) are working to identify a vaccine candidate that could offer a solution for all.Their main goal: concocting a live attenuated vaccine that would contain enough of the virus' properties to elicit a protective antibody response, but to a weak enough degree that the virus itself could not be transmitted sexually among humans, or, through blood via mosquito bites, to the main vector itself.Those risks make nailing the right formulation crucial because, unlike other illnesses for which these vaccines have been created, like the seasonal flu, Zika resides in several bodily fluids of infected individuals, and many of the virus' effects remain mysterious.


in like manner miamiherald

Paid volunteers would be infected with Zika for vaccine studies

Paid volunteers would be infected with Zika for vaccine studies
Paid volunteers would be infected with Zika for vaccine studies
2:55 Mayor Gimenez reacts to Zika cases found in Miami Beach Pause1:25 Miami Beach sanitation workers ramp up Zika mosquito prevention efforts1:40 Crowds show up for Wynwood Art Walk, regardless of Zika concerns1:52 NIH on Zika: "We're in a race of time to get best vaccine"1:24 CDC Director Dr. Tom Frieden details anti-Zika efforts in Miami1:58 Rick Scott talks Zika in Wynwood0:40 How to stay safe from Zika virus0:49 Zika's sting closes a Wynwood business1:32 Zika worries in Wynwood1:20 Health officials work to contain Zika virus in Miami-Dade


not to mention news-medical

Cloned Zika virus could be used for development of attenuated vaccine

Cloned Zika virus could be used for development of attenuated vaccine
Cloned Zika virus could be used for development of attenuated vaccine
Stopping the explosive spread of Zika virus - which can lead to birth defects in babies born to infected mothers - depends on genetic insights gleaned through new tools and models.Researchers at the National Institutes of Health recently cloned an epidemic strain of the virus, creating a model that can help biologists develop and test strategies for stopping the pandemic.In the latest issue of mBio, the researchers reported that the cloned virus replicated successfully in multiple cell lines, including placental and brain cells - tissue particularly vulnerable to damage from Zika.


additionally medicalnewstoday

Zika clone promises to assist vaccine development

Zika clone promises to assist vaccine development
Zika clone promises to assist vaccine development
Research published this week in the journal mBio describes the creation of a Zika virus clone.Experts hope that this new development might help in the design and production of an effective vaccine.Could the end be in sight for Zika?


Minimizing risk poses unique challenges in Zika vaccine trials, scientists say

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