Broadly neutralizing HIV antibodies engineered to be better vaccine leads : medicalxpress

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Broadly neutralizing HIV antibodies engineered to be better vaccine leads

Broadly neutralizing HIV antibodies engineered to be better vaccine leads

Minimal mutation of HIV-1 broadly neutralizing antibodies to guide reductionist vaccine design.Credit: William Schief One approach to HIV vaccine development relies on broadly neutralizing antibodies (bnAbs) that protect against different circulating HIV strains.bnAbs have been isolated from HIV-infected individuals, but they are highly evolved and unusual antibodies.


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Stripped-down HIV antibodies could make better vaccine targets

Stripped-down HIV antibodies could make better vaccine targets

A possible shortcut to an effective HIV vaccine has been discovered in a new study led by top HIV scientists at The Scripps Research Institute.The approach yielded powerful antibodies modeled after those found in rare individuals infected with HIV.These antibodies, which broadly neutralize many strains of HIV, don't require the immune system to jump through as many hoops to produce.


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Scientists using neutralised HIV antibodies to develop effective vaccine

Scientists using neutralised HIV antibodies to develop effective vaccine

A staff member at St. Vincent's Hospital Centre for Immunology in Sydney removes archived plasma samples used for HIV research from a minus 80 degree Celsius (-112 Fahrenheit) freezer July 20, 2007.A staff member at St. Vincent's Hospital Centre for Immunology in Sydney removes archived plasma samples used for HIV research from a minus 80 degree Celsius (-112 Fahrenheit) freezer July 20, 2007.Reuters/Tim WimborneScientists from Scripps Research Institute are using neutralised HIV antibodies to develop a HIV vaccine cure.

Broadly neutralizing HIV antibodies engineered to be better vaccine leads